University of Applied Sciences of the Grisons works with guiding themes in which it offers teaching and further education, performs applied research and provides services. In doing so, it works in close cooperation with partners from the world of business and the general public. The focus areas of Applied Future Technologies, Alpine Region Development and Entrepreneurial Management should also highlight the renunciation of hierarchies and silo thinking and the reorientation towards networking and interdisciplinarity.

University of Applied Sciences of the Grisons has defined the following three guiding themes in its strategy: